Nosocomial spread of ESBL-positive Enterobacter cloacae co-expressing plasmid-mediated quinolone resistance Qnr determinants in one hospital in France.

نویسندگان

  • Anaïs Potron
  • Laurent Poirel
  • Sandrine Bernabeu
  • Xavier Monnet
  • Christian Richard
  • Patrice Nordmann
چکیده

Service de Bactériologie–Virologie, INSERM U914 ‘Emerging Resistance to Antibiotics’, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine et Université Paris-Sud, 78 rue du Général Leclerc, 94275 K.-Bicêtre cedex, France; Service de Réanimation Médicale, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine et Université Paris-Sud, 78 rue du Général Leclerc, 94275 K.-Bicêtre cedex, France

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منابع مشابه

High prevalence of plasmid-mediated quinolone resistance determinants in Enterobacter cloacae isolated from hospitals of the Qazvin, Alborz, and Tehran provinces, Iran.

INTRODUCTION Plasmid-mediated quinolone resistance (PMQR) is a growing clinical concern worldwide. The main aims of this study were to detect qnr-encoding genes and to evaluate the clonal relatedness of qnr-positive Enterobacter cloacae isolates. METHODS A total of 116 E. cloacae isolates that were not susceptible to quinolone were obtained from seven hospitals in Tehran, five hospitals in Qa...

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Prevalence of Plasmid-mediated Quinolone Resistance and Its Association with Extended-spectrum Beta-lactamase and AmpC Beta-lactamase in Enterobacteriaceae

BACKGROUND We investigated the prevalence of plasmid-mediated quinolone resistance and its association with extended-spectrum beta-lactamase (ESBL) and AmpC beta-lactamase in Enterobacteriaceae. METHODS A total of 347 non-duplicated isolates of Enterobacteriaceae were collected between August and October 2006 from 2 hospitals. Qnr determinant screening was conducted using PCR amplification, a...

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Investigation of plasmid-mediated quinolone resistance among isolates obtained in a Turkish intensive care unit.

The aim of this study was to search for three plasmid-encoded, quinolone-resistant determinants: qnrA, qnrB, and qnrS. Thus, 460 Gram-negative strains belonging to 11 different genera (clinical, 347; non-clinical, i.e., from a rectal swab, 113), of which 40% were ciprofloxacin-resistant, were recovered from patients in an intensive care unit at the Istanbul Medical Faculty, Turkey, in the years...

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Plasmid-mediated quinolone resistance in expanded spectrum beta lactamase producing enterobacteriaceae in Morocco.

INTRODUCTION Although independently acquired, plasmid-mediated quinolone resistance appears to be linked with extended-spectrum or AmpC-type beta-lactamases. Since no data are available in African countries, the prevalence of qnr genes at the University Hospital Ibn Rochd, Casablanca, Morocco, was investigated. METHODOLOGY Between October 2006 and March 2007, the following 39 randomly selecte...

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Prevalence of Plasmid-Mediated Quinolone Resistance and Aminoglycoside Resistance Determinants among Carbapeneme Non-Susceptible Enterobacter cloacae

BACKGROUND Simultaneous resistance to aminoglycosides and fluoroquinolones in carbapeneme non-susceptible (CNS) isolates will inevitably create problems. The present study was performed to characterize the prevalence of the plasmid-mediated quinolone resistance determinants (QRDs) and aminoglycoside resistance determinants (ARDs) among the CNS Enterobacter cloacae (E. cloacae) isolates in a Chi...

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عنوان ژورنال:
  • The Journal of antimicrobial chemotherapy

دوره 64 3  شماره 

صفحات  -

تاریخ انتشار 2009